Abnormal red blood cell- TERMINOLOGY


Difference between Spur cell ( Acanthocytes) and Burr cell (Echinocytes)

Acanthocytes

always pathological
multiple and randomly space irregular projection -spiny erythrocytes
Poikilocyte with 3-10 surface projection
in liver disease, hemangiosarcoma, lipid metabolism in dogs
chg in rbc membrane associate with high cholesterol content of membrane expand outer lipid layer

spiny projection
Image result for spur cells

Echinocytes -Burr cell
-not always pathological
-evenly displace spicules -9-30 spikes
-crenation,drying artefact of erythroid cell ,appear projection
-Uremia, glomerulonephritis, lymphoma, IMHA
Image result for burr cells

Basophilic strippling
-basophilic granules in cytoplasm of rbc, -spontaneous aggregation of ribosome and polyribosome in RBC
-Blue dot on Romanowsky stained RBC
-Lead toxicity in abscense anemia, in dog
-regenerative anemia

Image result for basophilic stippling

CODOCYTES=
-cell with increase SA per unit, central rounded area surround by clear zone without pigment
-increase amt of cholesterol-increase surface area of rbc membrane,
-Disease- iron deficiency, cholestatic liver disease, post-splenectomy
-Obstructive jaundice, Asplenism, Regenerative anemia,
Image result for codocyte

Cholestatic-obstructive jaundice, liver cell unable transport bilirubin through hepatic bile membrane,damage biliary duct
Image result for cholestatic jaundice
Schistocytes
-RBC fragment due PHYSICAL DAMAGE
-DIC, GN, hemangiosarcoma
Image result for schistocytes

Dacrocytes- tear drop shaped rbc
-Iron def state,
-Myelofibrosis (scarring of bone marrow)
-Myelophthisisdisplacement of hemopoietic bone-marrow tissue by fibrosis, tumors, or granulomas
Image result for dacrocytesImage result for dacrocytes

GHOST CELL-
PALE RBC WITH NO/MIN HB
IMHA, intravascular hemolysis, in vitro hemolysis, RBC lysis
Image result for ghost cell rbc

Spherocytes
-lost biconcave, central pallor, bc round like sphere
-IMHA, anaplasmosis, Mycoplasma haemofelis, penicillin horse
Image result for spherocytes
Abnormal red blood cell- TERMINOLOGY Abnormal red blood cell- TERMINOLOGY Reviewed by Dream Investor on February 16, 2020 Rating: 5

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